The evolution of a tuberculosis (TB) infection towards active disease is driven by a combination of factors mostly related to the host response.The equilibrium between control of the bacillary load and the pathology generated is crucial as regards preventing the growth and proliferation of TB lesions.In addition, some experimental evidence suggests
Global climate change is correlated not only with variation in extinction rates, but also with speciation rates.However, few mechanisms have been proposed to explain how climate change may have driven the emergence of new Stoneware Plate evolutionary lineages that eventually became distinct species.Here, we discuss a model of range extension follow
The BTB domain is a conserved protein-protein interaction motif.In this study, we identified 56 BTB domain-containing protein genes in the silkworm, in addition to 46 in the honey bee, 55 in the red flour beetle, and 53 in the monarch butterfly.Silkworm BTB protein genes were classified into nine subfamilies Collectibles according to their domain a
Wilms tumor (WT) is an embryonic kidney cancer, for which histone acetylation might be a therapeutic target.LBH589, a novel targeted agent, suppresses histone deacetylases in many tumors.This study investigated the antitumor activity of LBH589 in SK-NEP-1 and G401 cells.SK-NEP-1 and G401 cell growth was assessed by CCK-8 and in nude mice experiment